Valex CR 500 Tablet

Sodium Valproate Tablets may be Given Once or Twice Daily. Sodium Valproate Syrup should be given in Divided Doses.
Epilepsy-Adults: Initially 600 mg Daily Given in 2 Divided Doses, Preferably After Food, Increasing by 200 mg/day at 3-Day Intervals to a Maximum of 2.5 g Daily in Divided Doses Until Control of Seizure is Achieved. Usual Maintenance Dose is 1-2 g Daily (20-30 mg/kg Daily)
Children (Up to 20 kg): Initially 20 mg/kg Daily in Divided Doses, may be Increased Provided Plasma Concentrations Monitored (Above 40 mg/kg Daily also Monitor Clinical Chemistry and Hematological Parameters).
Children (Over 20 kg): Initially 400 mg daily in divided doses increased until control (usually in the range of 20-30 mg/kg daily) Maximum 35 mg/kg Daily.
Febrile Convulsion: 20-30 mg/kg/day in 3 Divided Doses.
Bipolar Disorder: Initially 20-30 mg/kg/day in 2-3 Divided Doses; Adjust Dosage in 3-5 Days. Maintenance Dosage is 1000-2000 mg/day.
Prophylaxis of Migraine: 300 mg Twice Daily, Although some may Require 1000 mg Daily.