Anti-Ulcerant Dosage & Administration: The Recommended Adult Oral Dose for Reducing the Risk of NSAID-Induced Gastric Ulcers: 200 mcg Misoprostol Four Times Daily with Food. If this Dose cannot be Tolerated, a Dose of 100 mcg can be Used. Misoprostol should be Taken for the Duration of NSAID Therapy as Prescribed by the Physician. Misoprostol should be Taken with a Meal, and the Last Dose of the Day should be at Bedtime.
Renal Impairment: Adjustment of the Dosing Schedule in Renally Impaired Patients is not Routinely Needed, but Dosage can be Reduced if the 200 mcg Dose is not Tolerated.
Gynecological Dosage & Administration-Induction of Labor: 25 mcg Vaginally 6 Hourly or 50 mcg Orally 4 Hourly.
Postpartum Hemorrhage (PPH) Prophylaxis: 400 mcg to 600 mcg Orally or Rectally Immediately Following Delivery of the Child.
Postpartum Hemorrhage (PPH) Treatment: 1000 mcg Rectally or, 200 mcg Orally with 400 mcg Sublingually.
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