Cortan 20 Tablet

The Initial Dosage of Prednisolone may Vary from 5 mg to 60 mg Daily Depending on the Disorder being Treated. Divided Daily Dosage is Usually Used. The Appropriate Individual Dose must be Determined by Trial and Error and Must be Reevaluated Regularly According to Activity of the Disease. In General, Initial Dosage shall be Maintained or Adjusted Until the Anticipated Response is Observed. The Dose should be Gradually Reduced Until the Lowest Dose, which will Maintain an Adequate Clinical Response is Reached. The 5 mg and 2 mg Tablets are Preferably Used for Tapering Dose. During Prolonged Therapy, Dosage may Need to be Temporarily Tncreased During Periods of Stress or During Exacerbations of the Disease. When the Drug is to be Stopped, it Must be Withdrawn Gradually and not Abruptly.
Intermittent Dosage Regimen: A Single Dose of Prednisolone in the Morning on Alternate Days or at Longer Intervals is Acceptable Therapy for Some Patients. When this Regimen is Practical, the Degree of Pituitary-Adrenal Suppression can be Minimized.
Specific Dosage Guidelines: Allergic and Skin Disorders: Initial Doses of 5-15 mg Daily are Commonly Adequate.
Collagenosis: Initial Doses of 20-30 mg Daily are Frequently Effective. Those with More Severe Symptoms may Require Higher Doses.
Rheumatoid Arthritis: The Usual Initial Dose is 10-15 mg Daily. The Lowest Daily Maintenance Dose Compatible with Tolerable Symptomatic Relief is Recommended.
Blood Disorders and Lymphoma: An Initial Daily Dose of 15-60 mg is Often Necessary with Reduction After an Adequate Clinical or Hematological Response. Higher Doses may be Necessary to Induce Remission in Acute Leukaemia.
Tapering: Dosage should be Tapered Down with 5 mg and 2 mg Tablets After the Treatment Period.
Children: Acute Ssthma: Children Aged 18 Months to 12 years: 0.5-2 mg/kg/day (Max 40 mg) Once Daily for Up to a Total of 3 Days or Longer if Necessary. Prednisolone should be Taken in the Morning After Food. No Gradual Decrease of the Dose is Required. Children Aged 12-18 Years: 40-50 mg Once Daily for at Least 5 Days.
Other Indications for Children: Initial Dosage: 0.5 mg/kg/day in Three or Four Divided Doses After Food. This Dosage can be Doubled or Tripled if Necessary.
Maintenance Dosage: 0.125 to 0.25 mg/kg/day