Oral-Benign Gastric and Duodenal Ulcer: 20 mg Once Daily for 4 Weeks in Duodenal Ulceration, 8 Weeks in Gastric Ulceration; in Severe or Recurrent Cases, Dose to be Increased to 40 mg Daily; Maintenance Dose for Recurrent Duodenal Ulcer, 20 mg once Daily; in Prevention of Relapse in Duodenal Ulcer, 10-20 mg Daily.
NSAID-Associated Duodenal or Gastric Ulcer: 20 mg Once Daily for 4 Weeks, Continued for Further 4 Weeks, if not Fully Healed. 20 mg Once Daily is used as Prophylaxis in Patients with a History of NSAID-Associated Duodenal or Gastric Ulcers.
Gastro-Esophageal Reflux Disease: 20 mg Once Daily for 4 Weeks, Continued for Further 4-8 Weeks, if not Fully Healed; 40 mg Once Daily has been Given for 8 Weeks in Gastro-Esophageal Reflux Disease, Refractory to Other Treatment; Maintenance dose is 20 mg Once Daily.
Long-Term Management of Acid Reflux Disease: 10-20 mg Daily.
Acid-Related Dyspepsia: 10-20 mg Once Daily for 2-4 Weeks.
Prophylaxis of Acid Aspiration: 40 mg on the Preceding Evening, then 40 mg 2-6 Hours Before Surgery.
Zollinger-Ellison Syndrome: Initially 60 mg Once Daily; Usual Range 20-120 mg Daily (If Daily Dose is More Than 80 mg, 2 Divided Dose should be Used).
Helicobacter Pylori Eradication Regimen in Peptic Ulcer Disease: Omeprazole is Recommended at a Dose of 20 mg Twice Daily in Association with Antimicrobial Agents as Detailed Below: Amoxicillin 500 mg and Metronidazole 400 mg Both Three Times a Day for One Week, or Clarithromycin 250 mg and Metronidazole 400 mg Both Twice a Day for One Week, or Amoxicillin 1 g and Clarithromycin 500 mg Both Twice a Day for One Week.
Paeditaric Use in Severe Ulcerating Reflux Esophagitis (Child>1 Year): If Body-Weight 10-20 kg, 10-20 -mg Once Daily for 4-12 Weeks; if Body-Weight over 20 kg, 20-40 mg Once Daily for 4-12 Weeks.
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